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However, as previously reported, some phytochemicals increase the activity of L-glutamate decarboxylase (L-GAD), an enzyme responsible for the conversion of L-glutamate to GABA, and therefore, the level of GABA increases in the brain, especially in the hippocampus which leads to the activation of inhibitory pathway and help in the control of seizure (Kandeda et al., 2021a)

Stat Med 18(5):581599 Parke J, Holford NH, Charles BG (1999) A procedure for generating bootstrap samples for the validation of nonlinear mixed-effects population models

Elevated homocysteine levels have been associated with neurodegenerative diseases

The molecular mechanisms of glucose metabolism involve multiple steps, including glucose uptake, glycogenesis, glycogenolysis, glycolysis, and the tricarboxylic acid (TCA) cycle

doi: 10.1111/1346-8138.12717